This course explores the effectiveness of yoga interventions in pediatric oncology populations, emphasizing their potential benefits on quality of life and emotional well-being. Participants will learn about the main components of yoga sessions, including asanas (postures), breathing exercises (pranayama), and relaxation techniques. The course will review studies indicating that yoga can improve symptoms such as anxiety, depression, and physical function among young patients. Additionally, safety measures for yoga programs, including instructor training and consideration of children's comorbidities, will be discussed. The course will also cover the increase in the number of children engaging in yoga from 2012 to 2017, the physical and emotional benefits of yoga interventions, and commonly used measures for health-related quality of life outcomes. Nurses' roles in future studies of yoga in children with cancer will be highlighted, focusing on their ability to educate patients, families, and colleagues about the potential benefits of yoga.