JOPHON NCPD (May/June 2026) Patient Utilization and Satisfaction of Supportive Skin Care Products Among Children with Cancer Receiving Mitogen-Activated Protein Kinase Pathway Inhibitors-ARTICLE-Patient Utilization and Satisfaction of Supportive Skin Care Products Among Children with Cancer Receiving Mitogen-Activated Protein Kinase Pathway Inhibitors

ARTICLE-Patient Utilization and Satisfaction of Supportive Skin Care Products Among Children with Cancer Receiving Mitogen-Activated Protein Kinase Pathway Inhibitors

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This prospective, single-site study examined the use and acceptability of supportive skin-care products among children and young adults receiving mitogen-activated protein kinase (MAPK) inhibitors. Participants aged 0–21 received a free kit of skin, hair, and oral-care products with written and verbal instructions. Researchers assessed product use and satisfaction after three months, as well as skin-related quality of life (QOL) and medication adherence.<br /><br />Twenty participants enrolled, and 17 completed follow-up. Among respondents, 47% rated the kit excellent, 35% very good, and none rated it poor. Seventy-seven percent found the kit helpful and thought it should be provided before treatment begins. Most participants used and liked the core products, including moisturizers, cleanser, shampoo, and sunscreen; diluted bleach soaks and mouthwash were used less often.<br /><br />QOL scores did not change significantly. Participants who had not yet started MAPK therapy generally reported some worsening in skin-related QOL after treatment began, but the difference was not statistically significant. Nearly two-thirds reported missing no medication doses; skin effects were not cited as a reason for missed doses.<br /><br />The findings suggest that free skin-care kits are acceptable to patients and may support management of treatment-related skin effects. However, the small, single-center sample, limited racial diversity, and self-reported measures restrict the conclusions. Larger studies are needed to determine whether these kits improve QOL and to ensure products suit different skin tones and hair types.

Keywords

MAPK inhibitors

supportive skin care

pediatric oncology

young adults

skin-related quality of life

treatment adherence

moisturizers

sunscreen

oral care products

adverse skin effects